Associated Faculty
  Internal Users

home >>
Facility Citations


Publications Citing the PFD Facility


Chitayat, S., Kanelis, V., Koschinsky, M. L., and Smith, S. P. Nuclear Magnetic Resonance (NMR) Solution Structure, Dynamics, and Binding Properties of the Kringle IV Type 8 Module of Apolipoprotein(a) (2007) Biochemistry 46, 1732-1742. PM:17263558

Cuerrier, D., Moldoveanu, T., Campbell, R. L., Kelly, J., Yoruk, B., Verhelst, S. H., Greenbaum, D., Bogyo, M., and Davies, P. L. Development of calpain-specific inactivators by screening of positional-scanning epoxide libraries (2007) J.Biol.Chem. PM:17218315

Lin, F. H., Graham, L. A., Campbell, R. L., and Davies, P. L. Structural modeling of snow flea antifreeze protein (2007) Biophys.J. 92, 1717-1723. PM:17158562

Liu, Y. and Hill, B. C. Formamide probes a role for water in the catalytic cycle of cytochrome c oxidase (2007) Biochim.Biophys.Acta 1767, 45-55. PM:17184725

Singh, V. K., Zhou, Y., Marsh, J. A., Uversky, V. N., Forman-Kay, J. D., Liu, J., and Jia, Z. Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs (2007) Cancer Res. 67, 626-633. PM:17234772


Adams, J. J., Pal, G., Jia, Z., and Smith, S. P. Mechanism of bacterial cell-surface attachment revealed by the structure of cellulosomal type II cohesin-dockerin complex (2006) Proc.Natl.Acad.Sci.U.S.A 103, 305-310. PM:16384918

Bayly, R., Murase, T., Hyndman, B. D., Savage, R., Nurmohamed, S., Munro, K., Casselman, R., Smith, S. P., and LeBrun, D. P. Critical role for a single leucine residue in leukemia induction by E2A-PBX1 (2006) Mol.Cell Biol. 26, 6442-6452. PM:16914730

Boyd, J. G., Jahed, A., McDonald, T. G., Krol, K. M., Van Eyk, J. E., Doucette, R., and Kawaja, M. D. Proteomic evaluation reveals that olfactory ensheathing cells but not Schwann cells express calponin (2006) Glia 53, 434-440. PM:16345031

Crawley, S. W., De la Roche, M. A., Lee, S. F., Li, Z., Chityat, S., Smith, S. P., and Cote, G. P. Identification and characterization of an 8 kDa light chain associated with dictyostelium discoideum MyoB, a class I myosin (2006) J.Biol.Chem. PM:16415352

Eves, R., Webb, B. A., Zhou, S., and Mak, A. S. Caldesmon is an integral component of podosomes in smooth muscle cells (2006) J.Cell Sci. 119, 1691-1702. PM:16595550

Gujral, T. S., Singh, V. K., Jia, Z., and Mulligan, L. M. Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2B (2006) Cancer Res. 66, 10741-10749. PM:17108110

Masuda, S., Prosser, D. E., Guo, Y. D., Kaufmann, M., and Jones, G. Generation of a homology model for the human cytochrome P450, CYP24A1, and the testing of putative substrate binding residues by site-directed mutagenesis and enzyme activity studies (2006) Arch.Biochem.Biophys. PM:17224124

Prosser, D. E., Guo, Y., Jia, Z., and Jones, G. Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation (2006) Biophys.J. 90, 3389-3409. PM:16500955

Webb, B. A., Eves, R., and Mak, A. S. Cortactin regulates podosome formation: roles of the protein interaction domains (2006) Exp.Cell Res. 312, 760-769. PM:16434035

Webb, B. A., Zhou, S., Eves, R., Shen, L., Jia, L., and Mak, A. S. Phosphorylation of cortactin by p21-activated kinase (2006) Arch.Biochem.Biophys. PM:16854367

Ye, Q., Li, X., Wong, A., Wei, Q., and Jia, Z. Structure of calmodulin bound to a calcineurin Peptide: a new way of making an old binding mode(,) (2006) Biochemistry 45, 738-745. PM:16411749

Zhou, S., Webb, B. A., Eves, R., and Mak, A. S. Effects of tyrosine phosphorylation of cortactin on podosome formation in A7r5 vascular smooth muscle cells (2006) Am.J.Physiol Cell Physiol 290, C463-C471. PM:16162656


Adams, J. J., Webb, B. A., Spencer, H. L., and Smith, S. P. Structural characterization of type II dockerin module from the cellulosome of Clostridium thermocellum: calcium-induced effects on conformation and target recognition (2005) Biochemistry 44, 2173-2182. PM:15697243

Andrews, D., Mattatall, N. R., Arnold, D., and Hill, B. C. Expression, purification, and characterization of the Cu(A)-cytochrome c domain from subunit II of the Bacillus subtilis cytochrome caa(3) complex in Escherichia coli (2005) Protein Expr.Purif. 42, 227-235. PM:15907384

De la Roche, M. A., Mahasneh, A., Lee, S. F., Rivero, F., and Cote, G. P. Cellular distribution and functions of wild-type and constitutively activated Dictyostelium PakB (2005) Mol.Biol.Cell 16, 238-247. PM:15509655

Gauthier, S. Y., Marshall, C. B., Fletcher, G. L., and Davies, P. L. Hyperactive antifreeze protein in flounder species. The sole freeze protectant in American plaice (2005) FEBS J. 272, 4439-4449. PM:16128813

Graham, L. A. and Davies, P. L. Glycine-rich antifreeze proteins from snow fleas (2005) Science 310, 461. PM:16239469

Imriskova-Sosova, I., Andrews, D., Yam, K., Davidson, D., Yachnin, B., and Hill, B. C. Characterization of the Redox and Metal Binding Activity of BsSco, a Protein Implicated in the Assembly of Cytochrome c Oxidase (2005) Biochemistry 44, 16949-16956. PM:16363808

Marshall, C. B., Chakrabartty, A., and Davies, P. L. Hyperactive Antifreeze Protein from Winter Flounder Is a Very Long Rod-like Dimer of {alpha}-Helices (2005) J.Biol.Chem. 280, 17920-17929. PM:15716269

Ravulapalli, R., Diaz, B. G., Campbell, R. L., and Davies, P. L. Homodimerization of calpain 3 penta-EF-hand domain (2005) Biochem.J. 388, 585-591. PM:15660530

Scotter, A. J., Kuntz, D. A., Saul, M., Graham, L. A., Davies, P. L., and Rose, D. R. Expression and purification of sea raven type II antifreeze protein from Drosophila melanogaster S2 cells (2005) Protein Expr.Purif. PM:16330225

Singh, V. K. and Jia, Z. Refolding and one-step purification of recombinant human ARA70 over-expressed in Escherichia coli (2005) Protein Expr.Purif. 39, 283-287. PM:15642480

Tripodi, K. E., Turner, W. L., Gennidakis, S., and Plaxton, W. C. In vivo regulatory phosphorylation of novel phosphoenolpyruvate carboxylase isoforms in endosperm of developing castor oil seeds (2005) Plant Physiol 139, 969-978. PM:16169958

Turner, W. L., Knowles, V. L., and Plaxton, W. C. Cytosolic pyruvate kinase: subunit composition, activity, and amount in developing castor and soybean seeds, and biochemical characterization of the purified castor seed enzyme (2005) Planta 222, 1051-1062. PM:16049677

Webb, B. A., Eves, R., Crawley, S. W., Zhou, S., Cote, G. P., and Mak, A. S. PAK1 Induces Podosome Formation in A7r5 Vascular Smooth Muscle Cells in a PIX-dependent Manner (2005) Am.J.Physiol Cell Physiol 289, C898-C907. PM:15944209

Ye, Q., Singh, V. K., Blonde, J. D., and Jia, Z. Crystallization and preliminary X-ray analysis of the GST-fused human Bri3 N-terminal domain (2005) Acta Crystallogr.F. F61, 62-64.

Ye, Q., Imriskova-Sosova, I., Hill, B. C., and Jia, Z. Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins (2005) Biochemistry 44, 2934-2942. PM:15723536

Zheng, J., Singh, V. K., and Jia, Z. Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis (2005) Structure.(Camb.) 13, 1511-1520. PM:16216582

Zhou, S., Webb, B. A., Eves, R., and Mak, A. S. Effects of Tyr-phosphorylation of cortactin on podosome-formation in A7r5 vascular smooth muscle cells (2005) Am.J.Physiol Cell Physiol 290, 463-471. PM:16162656


Adams, J. J., Jang, C. J., Spencer, H. L., Elliott, M., and Smith, S. P. Expression, purification and structural characterization of the scaffoldin hydrophilic X-module from the cellulosome of Clostridium thermocellum (2004) Protein Expr.Purif. 38, 258-263. PM:15555941

Ancsin, J. B. and Kisilevsky, R. A binding site for highly sulfated heparan sulfate is identified in the N terminus of the circumsporozoite protein: significance for malarial sporozoite attachment to hepatocytes (2004) J.Biol.Chem. 279, 21824-21832. PM:15007056

Becker, L., Cook, P. M., and Koschinsky, M. L. Identification of sequences in apolipoprotein(a) that maintain its closed conformation: a novel role for apo(a) isoform size in determining the efficiency of covalent Lp(a) formation (2004) Biochemistry 43, 9978-9988. PM:15287725

Becker, L., Cook, P. M., Wright, T. G., and Koschinsky, M. L. Quantitative evaluation of the contribution of weak lysine-binding sites present within apolipoprotein(a) kringle IV types 6-8 to lipoprotein(a) assembly (2004) J.Biol.Chem. 279, 2679-2688. PM:14581473

Diaz, B. G., Moldoveanu, T., Kuiper, M. J., Campbell, R. L., and Davies, P. L. Insertion sequence 1 of muscle-specific calpain, p94, acts as an internal propeptide (2004) J.Biol.Chem. 279, 27656-27666. PM:15073171

Hosfield, C. M., Elce, J. S., and Jia, Z. Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides (2004) J.Mol.Biol. 343, 1049-1053. PM:15476820

Moldoveanu, T., Campbell, R. L., Cuerrier, D., and Davies, P. L. Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site (2004) J.Mol.Biol. 343, 1313-1326. PM:15491615

Moldoveanu, T., Jia, Z., and Davies, P. L. Calpain activation by cooperative Ca2+ binding at two non-EF-hand sites (2004) J.Biol.Chem. 279, 6106-6114. PM:14581465

Pellegrino, M., Furmaniak-Kazmierczak, E., LeBlanc, J. C., Cho, T., Cao, K., Marcovina, S. M., Boffa, M. B., Cote, G. P., and Koschinsky, M. L. The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells (2004) J.Biol.Chem. 279, 6526-6533. PM:14660654

Rees-Milton, K. J., Terry, D., and Anastassiades, T. P. Hyperglycosylation of fibronectin by TGF-beta1-stimulated chondrocytes (2004) Biochem.Biophys.Res.Commun. 317, 844-850. PM:15081417

Singh, P., Salih, M., Leddy, J. J., and Tuana, B. S. The muscle-specific calmodulin-dependent protein kinase assembles with the glycolytic enzyme complex at the sarcoplasmic reticulum and modulates the activity of glyceraldehyde-3-phosphate dehydrogenase in a Ca2+/calmodulin-dependent manner (2004) J.Biol.Chem. 279, 35176-35182. PM:15199064

Westlake, C. J., Payen, L., Gao, M., Cole, S. P., and Deeley, R. G. Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region (2004) J.Biol.Chem. 279, 53571-53583. PM:15459206


Becker, L., Webb, B. A., Chitayat, S., Nesheim, M. E., and Koschinsky, M. L. A ligand-induced conformational change in apolipoprotein(a) enhances covalent Lp(a) formation (2003) J.Biol.Chem. 278, 14074-14081. PM:12566443

Blonde, J. D. and Plaxton, W. C. Structural and kinetic properties of high and low molecular mass phosphoenolpyruvate carboxylase isoforms from the endosperm of developing castor oilseeds (2003) J.Biol.Chem. 278, 11867-11873. PM:12519778

De la Roche, M. A., Lee, S. F., and Cote, G. P. The Dictyostelium class I myosin, MyoD, contains a novel light chain that lacks high-affinity calcium-binding sites (2003) Biochem.J. 374, 697-705. PM:12826013

Hill, B. C., Becker, L., Anand, V., Kusmierczyk, A., Marcovina, S. M., Rahman, M. N., Gabel, B. R., Jia, Z., Boffa, M. B., and Koschinsky, M. L. A role for apolipoprotein(a) in protection of the low-density lipoprotein component of lipoprotein(a) from copper-mediated oxidation (2003) Arch.Biochem.Biophys. 412, 186-195. PM:12667482

Suntharalingam, P., Spencer, H., Gallant, C. V., and Martin, N. L. Salmonella enterica serovar typhimurium rdoA is growth phase regulated and involved in relaying Cpx-induced signals (2003) J.Bacteriol. 185, 432-443. PM:12511488